1. Education
Send to a Friend via Email
You can opt-out at any time. Please refer to our privacy policy for contact information.

Discuss in my forum

Stages of Mitosis


3 of 5



In metaphase, the spindle fully develops and the chromosomes align at the metaphase plate (a plane that is equally distant from the two spindle poles).

View image of a cell in metaphase.

Changes that occur in a cell during metaphase:
  • The nuclear membrane disappears completely.

  • In animal cells, the two pair of centrioles align at opposite poles of the cell.

  • Polar fibers (microtubules that make up the spindle fibers) continue to extend from the poles to the center of the cell.

  • Chromosomes move randomly until they attach (at their kinetochores) to polar fibers from both sides of their centromeres.

  • Chromosomes align at the metaphase plate at right angles to the spindle poles.

  • Chromosomes are held at the metaphase plate by the equal forces of the polar fibers pushing on the centromeres of the chromosomes.

Mitosis Overview, Images, and Quiz

  1. About.com
  2. Education
  3. Biology
  4. Cell Biology
  5. Cell Division
  6. Mitosis
  7. Stages of Mitosis: Metaphase Overview

©2014 About.com. All rights reserved.