1. Education
Send to a Friend via Email

Discuss in my forum

Regina Bailey

Fragile X Syndrome and Autism

By February 21, 2013

Follow me on:

Neuron
Image Credit: Cell Image Library

Researchers from the Washington University School of Medicine in St. Louis have identified the method by which fragile X syndrome alters signals between neurons in the brain. Fragile X syndrome is the result of a sex chromosome mutation on the X chromosome. The Fmr1 gene, located on the X chromosome, undergoes mutations that can result in inherited forms of autism, mental retardation, epilepsy, and developmental delays. According to the study, fragile X syndrome causes too many brain signals to be sent at once. This makes it more difficult for the brain to distinguish the important signals from the unnecessary signals.

The researchers discovered that the mutated Fmr1 gene causes neuronal axons to increase the amount of neurotransmitters released in the brain. According to senior author of the study, Vitaly Klyachko, "The axons are putting out much more neurotransmitter than they should, and we think this confuses the system and overloads the circuitry." The researchers contend that understanding how the signaling process in fragile X syndrome is altered is important to the development of new treatments for autism and other fragile X syndrome disorders.

Learn more about this study, see:

Comments

March 2, 2013 at 12:04 pm
(1) http://www.nationnews.com/member/35742/ says:

Hi i am kavin, its my first occasion to commenting anywhere, when i read this post i thought i could also create comment due to this sensible paragraph.

March 3, 2013 at 10:14 am
(2) www.ryanandshelbie.com says:

I think this is among the most important information for me.
And i am glad reading your article. But should remark on some general things, The web site style is perfect, the articles is really nice : D.
Good job, cheers

Leave a Comment


Line and paragraph breaks are automatic. Some HTML allowed: <a href="" title="">, <b>, <i>, <strike>
  1. About.com
  2. Education
  3. Biology

©2014 About.com. All rights reserved.